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Host Seth Meyers kicked off the 75th annual Golden Globes on Sunday night by addressing the elephant in the room: sexual harassment scandals in Hollywood.

Tune in after the telecast for The Hollywood Reporter and Hollywood Foreign Press Association's official aftershow, live on Twitter. "Good evening, ladies and remaining gentlemen", he grinned slash grimaced, breaking the ice as best he could.

Meyers wrapped up his monologue with a thank you to the women in the audience: "I look forward to whatever you'll be leading us into next".

"Harvey Weinstein isn't here tonight because, well, I heard rumors that he's insane and hard to work with", Seth, who is hosting the show, told the crowd during his opening monologue.

But don't worry, his former "SNL" "Weekend Update" Amy Poehler was there to keep his white male privilege in check when she called him out for "mansplaining".

"It's been years since a white man has been this nervous in Hollywood".

When the audience loudly reacted to the joke, Meyers added, "It'll sound like that".

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The protest that turned the Globes dark on the fashion front had been anticipated for days after a call for massive reform following the downfall of movie mogul Harvey Weinstein and numerous others accused of sexual misconduct in Hollywood, media, fashion, tech, publishing and other industries.

He said when he heard the premise of the fantasy-drama The Shape of Water, a movie that leads the night with seven Golden Globe nominations, "I have to admit when I first heard about a film when a naive young girl falls in love with a disgusting sea monster I thought, 'Oh man, not another Woody Allen movie'". Host Seth Meyers said "Hollywood Foreign Press" sounds like three words created to infuriate Donald Trump.

"I hope he can do a Southern accent, because Kevin Spacey sure couldn't" Meyers continued, referring to Spacey's nefarious South Carolinian character of President Frank Underwood on House of Cards as more groans came from the crowd and the camera panned to show a chuckling Plummer. It is a gay coming-of-age film.

From there, the show moved on with Gal Gadot and Dwayne Johnson awarding Nicole Kidman with the first win of the night for best performance by an actress in a limited series or a motion picture made for television for her role on "Big Little Lies". "WHY?" and also, "I forgot to say "alleged". because i know better". I'm not even the most powerful Seth in the room tonight.

He then took on some of the powerful men who were revealed to be serial harassers and assailants this year.

Hosting the first awards show of 2018, Meyers had a daunting task ahead of him.