Investors watch the rising interest rates closely.
Anthem's strong results and forecast sent its shares up 1.5 percent and also boosted other health insurers, a day after the group and other health stocks were hit by news of Amazon's healthcare plans.
The U.S. Treasury announced Wednesday morning that it was increasing the amount issued of 10-year and 30-year bonds by $1 billion, which comes at a time when the Fed is decreasing the bonds it purchases. End-of-month portfolio rebalancing, anticipation over interest rates, oil prices, a too-good-to-be true earnings season - even questions over Apple's iPhone - seemed to set in at the same time. Express Scripts, McKesson, Humana, Cigna, UnitedHealth, CVS Health and Centene were down between 5.3 percent and 7.2 percent. At 9:41 am ET (1441 GMT), the Industrial Average was down 230.55 points, or 0.87 per cent, at 26,208.93, the S&P 500 was down 20.52 points, or 0.71 per cent, at 2,833.01. They were the worst performers in the S&P 500 a year ago and led the index lower today, each falling around 1 percent. The January meeting is the last for outgoing Chairwoman Janet Yellen who will be replaced by fellow board member Jerome Powell on February 3.
European stocks ended mostly lower, (http://www.marketwatch.com/story/european-stocks-inch-higher-but-gains-kept-in-check-by-43-capita-plunge-2018-01-31) while Asian markets finished mixed.
Fourth-quarter earnings for the S&P 500 are now seen growing 13.2 percent, up from 12 percent at the beginning of the year, according to Thomson Reuters data.
Asian stocks were mixed Wednesday after Wall Street recorded its biggest decline since August. Eli Lilly lost $3.92, or 4.6 percent, to $82.17, while Gilead Sciences gave up $3.10, or 3.6 percent, to $84.19. The stock was down more than any other company in the S&P 500, shedding $2.68 to $25.64. The stock slid $1.54 to $58.64. Inflation is likely to stabilize around its 2% target, said the central bank, dropping prior language about a recent decline in prices. They had risen about 2 per cent in premarket trading after the company's quarterly results and full-year forecasts beat expectations.
Alleged Toronto serial killer facing 3 new counts of murder
When CNN reached Couse, he declined to comment. "He's an alleged serial killer and he's taken some steps to cover his tracks". Investigators believe there may be more victims, and are scouring approximately 30 properties linked to McArthur.
Killer whale learns to mimicing words
And since this was just the one whale, the researchers are unsure whether there are more copy-cat killer whales in the wild. Indeed, Wikie's reproduction of the word "hello" sounds practically human . "But we were surprised by how close it was".
Harden scores 60 as Rockets topple Magic
Stanley Johnson scored a career-high 26 points, and Detroit snapped an eight-game losing streak by defeating visiting Cleveland. But to get one and also get 60 points is ridiculous.
The prospect for stronger economic growth, both in the USA and overseas, has helped drive bond yields higher in recent months. We are not saying yields are going to scream higher. A rise in yields makes borrowing cash more expensive.
CURRENCY: The dollar gained to 108.97 yen from 108.78 yen.
AT&T Verizon and Sprint were down between 1.1 per cent and 1.6 per cent on reports that President Donald Trump's national security team is looking at options such as a government-built super-fast 5G wireless network.
MARKETS OVERSEAS: Germany's DAX fell 0.2 percent, while France's CAC 40 gained less than 0.1 percent. "We've gone the longest in over 100 years without a 5 percent pullback, so we think this is overdue".
Hong Kong's Hang Seng has been the best performer for the year so far with a rise of nearly 11 per cent, while Shanghai blue chips ran into profit-taking on Monday.