However, Sevilla have already given a clear demonstration of how risky they are away from home in Europe.
Bayern missed out on the semi-finals a year ago, losing to Real in the quarter-finals, and in 2011 when they were knocked out in the last 16 by Inter Milan.
Meanwhile, neither Lionel Carole nor Miguel Layun are eligible for the Champions League.
"Sevilla are in the last chance saloon and a risky team". Winning 2-1 away from home is great, but it's only half-time. They did very well to win in Manchester [against United] and we know we have to perform at our best.
Bayern Munich put in a professional performance as a goalless draw against 10-man Sevilla sealed their place in the Champions League semi-finals.
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Sevilla remain an extremely inconsistent side and since their memorable 2-1 win at Manchester United in the previous round, they have failed to win any of the four matches they have contested. "For one reason, they have to search for something to score goals in our stadium", Heynckes told press on Tuesday.
Hargreaves, who played for the Bavarians between 2000 and 2007, has backed his former club to go all the way in Europe, especially with the experienced leadership of manager Jupp Heynckes to guide them. - This is the first occasion since 2010 that only one Spanish side have reached the Champions League semi-finals, with the previous seven campaigns featuring exactly two.
He said: "It's the pinnacle to play at this level and really special". Arturo Vidal remains a major doubt, while the likes of James Rodriguez and Robert Lewandowski are likely to be rested once again.
The tightest of the Champions League ties, the victor will join Liverpool and Roma, as well as one of Real Madrid or Juventus in the semi-final draw on Friday.