"#Kiepenkerl There are dead and injured. We wish we were able to console them".
Authorities said a motive remains unclear.
Outside Muenster University Hospital, a long queue has formed of people wanting to give blood after the hospital put an urgent call out for donations.
Muenster Police President Hajo Kuhlisch says "we are now focusing our investigations on getting a comprehensive picture of the perpetrator's behavior in the weeks (before the crash) to find out his motivation for this frightful act". Jan Schoessler, who was among those in line, said dozens of people were waiting shortly after doors opened at 7 p.m.
While stressing that the investigation was still ongoing, Reul said the perpetrator was believed to be a German citizen "and not, as has been claimed everywhere, a refugee or something like that".
"We continue investigating in all directions", Seehofer told reporters.
He then fatally shot himself. "My thanks go to all the responders at the scene".
The impact of the crash was so violent that the van did not stop until it hit the pub's stone wall. "This must be carefully investigated", he said after paying his respects to the victims with national Interior Minister Horst Seehofer and state premier Armin Laschet.
Local media have identified the man as an industrial designer who had been suffering psychological problems, but police would not confirm the details. "That is our current task", Bode said.
The driver of the van was not identified by name.
The driver committed suicide inside the van, police said.
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Armed Police officers are seen at the scene when several people were killed and injured when a vehicle ploughed into pedestrians in Muenster, western Germany on April 7, 2018.
"I'm shocked to find out about the awful incident in Muenster", he said. Our sympathy is with the relatives of those who were killed. It is located in the historical part of the city. His identity is not yet known.
The newspaper said the four men were linked to Anis Amri, a Tunisian man with Islamist militant ties who killed 12 people in an attack in Berlin in December 2016 when he hijacked a truck and drove it into a crowded marketplace. Rescue personnel, emergency doctors and firefighters were among those attending the service.
But authorities appeared near-certain that there was no Islamist connection to the violence in the historic center of Muenster. The second in NY in 2017, when a driver ploughed a pickup truck down a crowded bike path along the Hudson River in Manhattan, killing eight people and injuring 11 before being shot by a police officer. He said the driver's identity was not yet known. It was a warm sunny afternoon, one of the first nice days of spring, and many people were out, Bild editor Julian Reichelt told CNN.
Two of those injured were Dutch, including one in a critical condition.
Meanwhile, investigators are still trying to establish the motive for the ramming. "Please avoid the area".
Chancellor Angela Merkel said in a statement she was "deeply shaken".
Witnesses said people ran away screaming from the city square after the crash.
The half-marathon was being guarded by some 630 police officers, German news agency dpa reported.
The incident came on Saturday after a grey minivan rammed into a dining area outside the Kiepenkerl cafe in Muenster, a popular venue for locals and tourists.